Category: Basic Science & Research

The Regenerative Marriage Between High-Density Platelet-Rich Plasma and Adipose Tissue

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations, Latest News, PRP & Adipose, Regenerative Potential & Mechanisms of Nanofat, Wound Healing

Date Published: 27 February 2025 Everts et al., investigate the synergistic effects of combining HD-PRP with adipose tissue, particularly looking at the role of t-SVF in these effects. They find that the combination multicellular approach using both of these cellular biological products leads to improved tissue repair, regeneration and, wound healing. The article was published […]

Nanofat applications: from clinical esthetics to regenerative research: Potential applications of nanofat in tissue regeneration with a focus on wound healing and vascularization

Posted in Basic Science & Research, Regenerative Potential & Mechanisms of Nanofat, Wound Healing

June 2019 Lisanne Grünherz et al. published a study titled “Nanofat applications: from clinical esthetics to regenerative research: Potential applications of nanofat in tissue regeneration with a focus on wound healing and vascularization” in Current Opinion in Biomedical Engineering. They “propose that nanofat should also be considered for use in translational research” and that “nanofat […]

Concentrated nanofat: a modified fat extraction promotes hair growth in mice via the stem cells and extracellular matrix components interaction

Posted in Adipose Tissue Complex, Basic Science & Research, Dermatology, Hair Loss, Office Based Aesthetic Medicine

September 2020 Zehua Li et al. published a study titled “Concentrated nanofat: a modified fat extraction promotes hair growth in mice via the stem cells and extracellular matrix components interaction” in The Annals of Translational Medicine. The study investigated the mechanisms and effects of fat grafting on hair growth in a mouse model and found […]

Boosting tissue vascularization: Nanofat as a potential source of functional microvessel segments

Posted in Basic Science & Research, Regenerative Potential & Mechanisms of Nanofat

February 2022 Andrea Weinzierl et al. published “Boosting tissue vascularization: Nanofat as a potential source of functional microvessel segments” in Frontiers in Bioengineering and Biotechnology. They investigate nanofat grafts in a murine dorsal skin fold chamber model and conclude that nanofat boosts tissue vascularization and that nanofat may represent a versatile resource for many applications […]

Discussion: Protein profiling of mechanically processed lipoaspirates: Discovering wound healing and antifibrotic biomarkers in nanofat

Posted in Basic Science & Research, Ideas & Innovations, Regenerative Potential & Mechanisms of Nanofat

November 2021 Dr. Ramon Llull wrote this discussion titled “Discussion: Protein profiling of mechanically processed lipoaspirates: Discovering wound healing and antifibrotic biomarkers in nanofat” in Plastic and Reconstructive Surgery. Click below to read the full article.

Nanofat: A Therapeutic Paradigm in Regenerative Medicine

Posted in Adipose Tissue Complex, Basic Science & Research, Regenerative Potential & Mechanisms of Nanofat

Madhan Jeyaraman et al. conducted this study exploring nanofat and its role as a therapeutic in regenerative medicine. Click below to access the full study.

Autologous Adipose-Derived Tissue Stromal Vascular Fraction (AD-tSVF) for Knee Osteoarthritis

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Knee, Orthopedics

Ibrahim Vargel, et. al. conducted this review of techniques involving autologous adipose-derived tissue stromal vascular fraction (AD-tSVF) for knee osteoarthritis in 2022. Click below to access the full study.

Use of Adipose-Derived Stem/Stromal Cells and It’s Native Bioactive Matrix

Posted in AD-cSVF, AD-tSVF, AD-MSC, Adipose Tissue Complex, Basic Science & Research, PRP & Adipose

SDARTs Faculty Member Dr. Robert Alexander published this study in 2016 exploring the use of adipose-derived stem/stromal cells and it’s native bioactive matrix in the field of biocellular regenerative medicine. THE KEY POINTS COVERED IN THIS PAPER ARE: Autologous Stem / Stromal Cells and Platelet Concentrates Guided to Targets. Combination of Cells & PRP concentrates […]

Impact of Aging on the Regenerative Properties of Bone Marrow, Muscle & Adipose-Derived Mesenchymal

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations

January 22nd, 2019 Olivia S. Beane, Vera C. Fonseca, Leroy L. Cooper, Gideon Koren, and Eric M. Darling look at the effects of aging on the regenerative properties of bone marrow-, muscle-, and adipose-derived mesenchymal stem/ stromal cells. The article was published in PLOS ONE. Want to learn more about this topic? Visit the SDARTs […]

Autologous Fat Grafting: Use of Closed Syringe Microcannula System for Enhanced Grafting

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Office Based Aesthetic Medicine, Techniques & Methods, Techniques & Methods for Fat Harvesting, Processing & Grafting

May 13th, 2019 SDARTs faculty member, Dr. Robert W Alexander, authored this overview on the use of a closed syringe, microcannula system for autologous fat grafting procedures. This study was published in Clinical, Cosmetic and Investigational Dermatology. READ THE STUDY NOW Want to learn directly from study author Robert W Alexander? Visit the SDARTs Online […]

Human Stromal Cell Aggregates Concentrate Adipose Tissue Constitutive Cell Population

Posted in AD-cSVF, AD-tSVF, AD-MSC, Adipose Tissue Complex, Basic Science & Research, Ideas & Innovations

January 28th, 2021 SDARTs faculty member, Ramon Lull, MD, PhD, et al, published a new study on “Human Stromal Cell Aggregates Concentrate Adipose Tissue Constitutive Cell Population by In Vitro DNA Quantification Analysis.” This study was published in the Plastic & Reconstructive Surgery Journal. Want to learn more from Dr. Ramon Llull? Visit the SDARTs […]

Comparison of Harvest and Processing Techniques for Fat Grafting and Adipose Stem Cell Isolation

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations, Techniques & Methods for Fat Harvesting, Processing & Grafting

March 14th, 2019 Study authors Christine Fisher, M.D., Tara L. Grahovac, M.D., Mark E. Schafer, Ph.D., Ron D. Shippert, M.D., Kacey G. Marra, Ph.D., and SDARTs faculty member J. Peter Rubin, M.D. compared techniques for processing and harvesting adipose tissue to determine effects on fat grafting outcomes. This study was published in the Plastic and […]

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Category: Basic Science & Research

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