Scientific Articles

The Regenerative Marriage Between High-Density Platelet-Rich Plasma and Adipose Tissue

Posted in AD-cSVF, AD-tSVF, AD-MSC, Basic Science & Research, Ideas & Innovations, Latest News, PRP & Adipose, Regenerative Potential & Mechanisms of Nanofat, Wound Healing

Date Published: 27 February 2025 Everts et al., investigate the synergistic effects of combining HD-PRP with adipose tissue, particularly looking at the role of t-SVF in these effects. They find that the combination multicellular approach using both of these cellular biological products leads to improved tissue repair, regeneration and, wound healing. The article was published […]

Is Patient Demand for Cellular Therapies Real?

Posted in Blog

A Personal Message from the Founder Having worked closely with practitioners across specialties for over three decades, I understand your skepticism. When physicians first explore regenerative therapies, they often ask: “Is the patient demand actually real, or just marketing hype?” After years collecting data from hundreds of practices, the evidence is undeniable—patients are actively seeking […]

Autologous lipoaspirate as a new treatment of vulvar lichen sclerosus: A review on literature

Posted in Clinical Trials & Pilot Studies, Gynecology & Female Sexual Wellness, Ideas & Innovations

Date Published: 11 March 2022 Nanouk van der Sluis et al., complete a review of pioneering studies already done to investigate the therapeutic effect of adipose tissue grafting for Lichen Sclerosus. In this review, they provide an overview of these studies and the proposed mechanisms-of-action of using fat grafting to treat LS. The article was published […]

LaMiNa: A Creative Synergistic Approach to Facial Rejuvenation

Posted in Combination with Energy Based Devices, Dermatology, Facial Rejuvenation & Skin Quality, Nanofat Microneedling, Office Based Aesthetic Medicine, Skin Rejuvenation

Date Published: 27 March 2023 Richard Brannon Claytor, et al., investigate the recovery potential of autologous nanofat when added to co-terminus CO2 lasering and microneedling treatment of fine lines and rhytids in facial skin. The article was published in Aesthetic Surgery Journal Open Forum.

Arthroscopy With Adipose-Derived Stromal Vascular Fraction Using a Selective Tissue Engineering Photo-Stimulation Technique for the Treatment of Mild to Moderate Knee Osteoarthritis

Posted in General Orthopedics, Knee, Orthopedics, Pain Management, Techniques & Methods for Fat Harvesting, Processing & Grafting

Date Published: 4 May 2024 José Paulo Gabbi Aramburu Filho et al., provide a step-by-step guide of arthroscopic treatment of mild to moderate knee osteoarthritis with photo-stimulated SVF via a “One S.T.E.P.” technique. The article was published in: Arthroscopy Techniques.

The Influence of Fat Grafting on Skin Quality in Cosmetic Foot Grafting: A Randomized, Cross-Over Clinical Trial

Posted in Clinical Trials & Pilot Studies, Dermatology, Foot & Ankle, Foot Fat Pad, Orthopedics, Skin Rejuvenation, Sports Medicine

Date Published: 10 July 2018 Stephanie E. Farber, et al., conducted a clinical trial with results indicating that pedal fat grafting resulted in a clinically significant and sustained increase in dermal thickness, as well as an improvement in skin quality. The article was published in Aesthetic Surgery Journal.

A New Minimally Invasive Procedure for Treating Plantar Heel Pain – Stromal Vascular Fraction Gel Grafting

Posted in Clinical Trials & Pilot Studies, Foot & Ankle, Foot Fat Pad, Orthopedics, Pain Management, Sports Medicine

Date Published: 5 Nov 2023 Bihua Wu, et al., investigated and found that stromal vascular fraction gel grafting is a safe, effective, and minimally invasive approach to treating plantar heel pain that actually worked to increase the thickness of the heel fat pad. The article was published in Annals of Plastic Surgery.

Autologous Nanofat Injection Combined with Fractional CO2 Laser in the Treatment of Atrophic Acne Scars

Posted in Clinical Trials & Pilot Studies, Combination with Energy Based Devices, Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Scar Treatment, Skin Scars & Acne Scarring

Date Published: 20 Mar 2024 Mahmoud A Rageh, et al. investigate the role of Nanofat in combination with fractional CO2 laser as a combined approach for treating atrophic acne scarring. The article was published in Clinical, Cosmetic and Investigational Dermatology.

Advancements in Regenerative Medicine for Aesthetic Dermatology: A Comprehensive Review and Future Trends

Posted in Aesthetic Dermatology (Facial Volume Restoration), Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Skin Rejuvenation

Date Published: 31 March 2024 Federica Trovato et al. provide a review of the principles and techniques of regenerative medicine and how they apply to cosmetic dermatology. The article was published in Cosmetic.

The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration

Posted in Office Based Aesthetic Medicine, Periorbital Rejuvenation

October 2019 Ehab Z. Azzam et al. published “The Efficacy of Autologous Nanofat Injection in the Treatment of Infraorbital Dark Colouration” in The Egyptian Journal of Plastic and Reconstructive Surgery. They investigated the effects of Nanofat injections for the treatment of infra-orbital dark circles and concluded that it provided a significant improvement in skin quality. […]

Nanofat Grafting: Basic Research and Clinical Applications

Posted in Clinical Trials & Pilot Studies, Dermatology, Facial Rejuvenation & Skin Quality, Office Based Aesthetic Medicine, Skin Rejuvenation, Techniques & Methods, Techniques & Methods for Fat Harvesting, Processing & Grafting

October 2013 Drs. Tonnard and Verpaele published a study titled “Nanofat Grafting: Basic Research and Clinical Applications” in Plastic and Reconstructive Surgery. The study evaluated the cellular contents of Nanofat and its efficacy in clinical applications which “showed remarkable improvements in skin quality 6 months postoperatively.” Click below to read the full study.

Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study

Posted in Clinical Trials & Pilot Studies, Elbow, Orthopedics

January 2021 Miguel Khoury et al. published “Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study” in The Journal of Experimental Orthopaedics. They studied the “effect of Adipose derived stromal cells (ASCs) injection as therapeutic procedure on the common extensor tendinopathy” and found significant clinical improvement and […]

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